The treatment of Graves' disease in children and adolescents
نویسندگان
چکیده
Graves' disease (GD) accounts for 10%-15% of thyroid disorders in children and adolescents. The use of antithyroid drugs as the initial treatment option in GD is well accepted. An average two years remission is achieved in about 30% of children treated with antithyroid drugs. However, the optimal treatment duration and the predictive marker of remission after antithyroid drug therapy are still controversial. Additionally, (131)I therapy and surgery are considered the option for treatment in children and adolescents with GD. We review the treatment options for pediatric GD and the possible determinants of remission and relapse on antithyroid drug treatment in children and adolescents.
منابع مشابه
Retrospective study of clinical course and treatment response in Graves’ disease [Persian]
In this report, the clinical course and treatment response of 210 patients with Grawes’ disease referred to the research institute for nuclear medicine were studied. The disease was more common in 3rd and 4th decades and more frequent in women (F/M=4). Treatment response with antithyroid drugs was about 50%, whereas 80% of the patients treated by I-131 showed positive response. There was ...
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This article is also accessible online at: http://BioMedNet.com/karger Graves’ disease (GD) is a rare disease in childhood and adolescence with only 1–5% of all patients being children. The incidence of juvenile GD ranges from 0.1 in young children to 3.0 in 100,000 in adolescents. Despite the numerous literature about therapy of GD in adults only a few investigations concerning children and ad...
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